延續著《花樣年華》中的角色，Tony飾演的周慕雲開始遊戲人間，遭遇了蘇麗珍、露露、王靜雯、白玲…女人在他眼中只是過眼雲煙。他埋首寫著一部關於2046的小說，故事裡有部神祕列車，主人翁Tak希望乘車去找回一段失去的愛。Tony在片中的演出更加成熟、層次飽滿，讓他再獲香港金像獎最佳男主角的肯定。

He was a writer, He thought he wrote about the future but it really was the past. In his novel, a mysterious train left for 2046 every once in a while. Everyone who went there had the same intention ... to recapture their lost memories. It was said that in 2046, nothing ever changed. Nobody knew for sure if it was true, because nobody who went there had ever come back - except for one. He was there. He chose to leave. He wanted to change.